How to programmatically check Generate automatic URL alias

If you want to programmatically check the Pathauto's Generate automatic URL alias checkbox you can do something like this:

use Drupal\pathauto\PathautoState;

$entity_type = 'node';
$entity_storage = \Drupal::entityTypeManager()->getStorage($entity_type);
$nodes = $entity_storage->loadMultiple();

foreach($nodes as $node) {
  $node->path->pathauto = PathautoState::CREATE;
  $node->save();
}

For terms just change the entity type to this:

$entity_type = 'taxonomy_term';

To uncheck the field instead of CREATE use SKIP constant:

$node->path->pathauto = PathautoState::SKIP;

In summary, the code snippets provided outline the process of programmatically toggling the automatic URL alias generation feature in Drupal using the Pathauto module.